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高血压是一种高龄人群中高发的慢性疾病,易引起冠心病、脑梗死、肾衰竭等病危因素,是严重威胁我国老年患者生命健康安全的慢性疾病之一。如何有效地控制血压是一个非常重要而现实的问题,研究人员一直在积极探索能够有效治疗高血压的新方案。近年来,经过研究者们共同探讨,联合用药成为治疗高血压的新方案。多项临床研究和分析发现,血管紧张素转换酶抑制剂(ACEI)和β受体阻滞剂(美托洛尔、卡维地洛等)的联合使用可以有效控制高血压,并且具有较少的不良反应。现将ACEI联合β受体阻滞剂治疗高血压的研究进展做一综述。
Hypertension is a chronic disease with a high incidence in the elderly. It is easy to cause the risk factors such as coronary heart disease, cerebral infarction and renal failure, and is one of the chronic diseases that seriously threaten the life, health and safety of elderly patients in our country. How to effectively control blood pressure is a very important and realistic issue, researchers have been actively exploring new programs that can effectively treat high blood pressure. In recent years, researchers have jointly explored the combination of drugs as a new program for the treatment of hypertension. A number of clinical studies and analyzes have found that the combined use of an angiotensin-converting enzyme inhibitor (ACEI) and a beta blocker (metoprolol, carvedilol, etc.) is effective in controlling hypertension and has fewer Adverse reactions. ACEI is now combined with β-blockers for the treatment of hypertension research is reviewed.