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目的随着现代新生儿医学的发展,机械通气的广泛应用,新生儿呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)已成为新生儿重症监护病房(NICU)备受关注的话题,本文重点分析和探讨亳州市人民医院新生儿呼吸机相关性肺炎(VAP)的发生情况、病原菌的种类、药敏监测及耐药性情况,为积极有效预防和治疗VAP提供一定的理论依据。方法回顾性分析118例机械通气超过48 h新生儿中符合VAP诊断标准的43例患儿,行下呼吸道分泌物及撤机时气管导管末端做细菌培养和药物敏感实验。结果 118例进行机械通气的患儿有43例发生了VAP,发生率36.44%,其中39例痰培养检测阳性。结论 VAP的发生率与插管次数、机械通气时间、胎龄、原发性肺部疾病等呈正相关,应针对性的对VAP患儿监控,并根据病原学结果合理用药。
Objective With the development of modern neonatal medicine and the widespread use of mechanical ventilation, neonatal ventilator-associated pneumonia (VAP) has become a topic of concern for neonatal intensive care unit (NICU). This article focuses on And explore the occurrence of neonatal ventilator-associated pneumonia (VAP) in Bozhou People’s Hospital, the types of pathogens, drug susceptibility monitoring and drug resistance, and provide a theoretical basis for the active and effective prevention and treatment of VAP. Methods A retrospective analysis of 118 cases of neonates with mechanical ventilation more than 48 h met VAP diagnostic criteria of 43 patients undergoing lower respiratory secretions and weaning endotracheal tube bacterial culture and drug sensitivity experiments. Results Among the 118 patients who underwent mechanical ventilation, 43 cases developed VAP with a rate of 36.44%, of which 39 cases were positive for sputum culture. Conclusions The incidence of VAP is positively correlated with the number of intubation, duration of mechanical ventilation, gestational age, primary pulmonary disease and so on. It should be monitored in VAP patients and be used rationally according to the etiology.