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A-80556是一种新的对革兰阳性菌和阴性菌及厌氧菌具有强效广谱抗菌活性氟喹诺酮.A-80556对革兰阳性菌的抗菌活性优于环丙沙星、氧氟沙星、洛美沙星及司帕沙星.A-80556对临床分离金葡菌的MIC_(90)为0.12μg/ml.对肺炎球菌的MIC_(90)为0.12μg/ml.A-80556对耐环丙沙星(MIC_(90)>128μg/ml)具有抗菌活性(MIC_(90)为4.0μg/ml),然而.其抗菌活性的重要性目前还未被认识.A-80556对大肠杆菌(MIC_(90),0.06μg/ml)及其他肠杆科细菌的抗菌活性略低于环
A-80556 is a new fluoroquinolone that has potent broad-spectrum antibacterial activity against Gram-positive and -negative and anaerobic bacteria. The antimicrobial activity of A-80556 against Gram-positive bacteria is superior to that of ciprofloxacin, (90) for clinical isolates of Staphylococcus aureus and 0.12μg / ml for pneumococci.A-80556 Anti-ciprofloxacin (MIC_ (90)> 128μg / ml) had antimicrobial activity (MIC_ (90) was 4.0μg / ml), but the importance of its antimicrobial activity is not yet known.A-80556 against Escherichia coli (MIC_ (90), 0.06μg / ml) and other Enterobacteriaceae antibacterial activity slightly lower than the ring