超氧化物岐化酶(Superoxide Dis-mutase,SOD)是体内氧代谢过程中产生的超氧阴离子自由基(?)的清除剂。在人体内,存在着CuZn-SOD(SOD-1)和Mn-SOD(SOD-2)两种SOD,前者见于细胞浆中,占体内SOD的主要部分,后者存在于细胞浆和线粒体中,体内含量很少。两者具有相同的催化(?)岐化反应的活性。近年来医学研究表明:很多疾病的病理过程均有(?)介导。所以,研究疾病过程中SOD的变化在临床医学中具有重要意义。一、(?)的病理作用 (?)具有强氧化活性,可起动自由基链式反应,对生物膜结构和核酸、脂类、蛋白质 Superoxide dismutase (SOD) is a scavenger of superoxide anion free radicals (?) Produced during the metabolism of oxygen in the body. In the human body, there are two SODs, CuZn-SOD (SOD-1) and Mn-SOD (SOD-2). The former is found in the cytoplasm and accounts for the major part of SOD in the body, which is present in the cytoplasm and mitochondria, In vivo content is small. Both have the same catalytic (?) Disproportionation activity. In recent years, medical studies have shown that many pathological processes are mediated by (?). Therefore, the study of changes in the course of disease SOD in clinical medicine is of great significance. First, the pathological role of (?) Has strong oxidative activity, can start free radical chain reaction, the biofilm structure and nucleic acid, lipid, protein