论文部分内容阅读
目的分析我院抗感染药物的临床应用趋势及常见细菌耐药情况,为临床合理应用抗感染药物提供有力证据。方法以金额、DDDS、日均药费为指标,对2005～2007年抗感染药物的使用情况进行分析,同时统计分析分离菌株对抗感染药物的敏感情况。结果3年来,全院抗感染药物出库金额呈上升趋势,而占全部药品出库金额比例下降。各亚类抗感染药物的应用中头孢菌素类应用额度最高,增长最快,青霉素类呈下降趋势,其它各类基本稳定。用药频度前15位中大多数为口服一线抗感染药,大多数的抗感染药物的耐药率逐年升高。结论我院抗感染药物应用广泛,使用基本合理。抗感染药物的用药频度与细菌耐药性呈正相关关系。
Objective To analyze the trend of clinical application of common anti-infective drugs in our hospital and the common bacterial resistance, providing strong evidence for clinical rational use of anti-infective drugs. Methods Using the amount of DDDS and average daily drug as an index, the use of anti-infectives from 2005 to 2007 was analyzed, and the susceptibility of isolates to anti-infective drugs was statistically analyzed. Results In the past three years, the hospital out of the total amount of anti-infective drugs increased, while the proportion of the total amount of drugs out of the library decreased. The application of cephalosporins in various sub-categories of anti-infectives has the highest application amount, the fastest growth rate, the decreasing trend of penicillins, and the other types are basically stable. Most of the top 15 medication frequency is oral first-line anti-infectives, and the majority of anti-infective drug resistance rates are increasing year by year. Conclusion Our hospital anti-infective drugs are widely used, the use of basic and reasonable. The frequency of anti-infective medication and bacterial resistance was positively correlated.