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目的对比分析单纯性热性惊厥(SFS)与复杂性热性惊厥(CFS)的临床特征。方法选取该院收治的230例热性惊厥(FS)患儿作为研究对象,根据临床分型将上述患儿分为SFS组(154例)与CFS组(76例),对比分析两组患儿的临床特征。结果 1两组患儿性别构成相比差异无统计学意义(P>0.05),SFS组首发年龄显著小于CFS组,差异有统计学意义(P<0.05)。2SFS组发作体温显著高于CFS组,惊厥发作频率、惊厥持续时间显著低于CFS组,差异有统计学意义(P<0.05)。3两组患儿血清总钙(TCa)相比差异无统计学意义(P>0.05)。SFS组血清钠(Na+)显著高于CFS组,血清肌酸激酶同工酶BB(CK-BB)、神经元特异性烯醇酶(NSE)、内皮素(ET)显著低于CFS组,差异有统计学意义(P<0.05)。4两组患儿脑脊液异常率、头颅CT异常率相比差异无统计学意义(P>0.05),SFS组脑电图异常率显著低于CFS组,差异有统计学意义(P<0.05)。5SFS组癫痫发生率显著低于CFS组,差异有统计学意义(P<0.05)。结论 SFS与CFS临床特征有着一定的区别,主要表现在体温、惊厥发作特征、血清生化指标、脑电图异常、预后等方面,这在FS患儿诊治过程中应给予重视。
Objective To compare and analyze the clinical features of simple febrile seizures (SFS) and complex febrile seizures (CFS). Methods Totally 230 children with febrile seizures (FS) were enrolled in this study. According to the clinical classification, the children were divided into SFS group (n = 154) and CFS group (n = 76) The clinical features. Results There was no significant difference in sex composition between the two groups (P> 0.05). The initial age of SFS group was significantly smaller than that of CFS group (P <0.05). The body temperature in the 2SFS group was significantly higher than that in the CFS group. The frequency of seizures and the duration of seizures were significantly lower than those in the CFS group (P <0.05). There was no significant difference in serum total calcium (TCa) between the two groups (P> 0.05). Serum sodium (Na +) in SFS group was significantly higher than that in CFS group, serum creatine kinase MB (CK-BB), neuron specific enolase (NSE) and endothelin There was statistical significance (P <0.05). There was no significant difference between the two groups (P> 0.05). The abnormal rate of EEG in SFS group was significantly lower than that in CFS group (P <0.05). The incidence of epilepsy in 5SFS group was significantly lower than that in CFS group (P <0.05). Conclusion The clinical features of SFS and CFS are different, mainly in the aspects of body temperature, seizure characteristics, serum biochemical indexes, EEG abnormalities and prognosis, which should be paid more attention in the diagnosis and treatment of FS.