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目的探讨复发性霉菌性阴道炎患者应用克霉唑阴道片与氟康唑联合治疗的疗效。方法 72例复发性霉菌性阴道炎患者为研究对象,按照随机数字表法分为观察组与对照组,每组36例。对照组使用克霉唑阴道片进行单独给药治疗,观察组在对照组治疗基础上联合氟康唑治疗。比较两组患者的治疗效果、各项临床症状消失时间及复发率。结果观察组患者的治疗总有效率(97.22%)明显高于对照组(80.56%),差异有统计学意义(P<0.05);观察组患者的外阴瘙痒、腰腹疼痛、白带异常及排尿痛消失时间均明显短于对照组,差异有统计学意义(P<0.05);观察组患者的复发率(5.71%)明显低于对照组(34.48%),差异有统计学意义(P<0.05)。结论复发性霉菌性阴道炎患者采用克霉唑阴道片与氟康唑联合治疗,可明显提高治疗效果,缩短临床症状消失时间,降低复发率,值得在临床治疗中应用推广。
Objective To investigate the curative effect of combined use of clotrimazole vaginal tablets and fluconazole in patients with recurrent fungal vaginitis. Methods 72 patients with recurrent fungal vaginitis were divided into observation group and control group according to the random number table method, with 36 cases in each group. The control group was treated with clotrimazole vaginal tablets alone, and the observation group was treated with fluconazole on the basis of the control group. The therapeutic effect of two groups were compared, and the disappearance time and recurrence rate of each clinical symptom were compared. Results The total effective rate (97.22%) in the observation group was significantly higher than that in the control group (80.56%), the difference was statistically significant (P <0.05). The patients in the observation group had genital itching, lumbar pain, vaginal discharge and urination (P <0.05). The recurrence rate of the observation group (5.71%) was significantly lower than that of the control group (34.48%), the difference was statistically significant (P <0.05) . Conclusions The treatment of recurrent fungal vaginitis with clotrimazole vaginal tablets combined with fluconazole can significantly improve the therapeutic effect, shorten the disappearance of clinical symptoms, reduce the recurrence rate, it is worth in the clinical application of the promotion.