用来自非洲Mseleni病人血清及居住疫区正常人和非疫区正常人血清,代替小牛血清,对兔和人关节软骨细胞培养,观察细胞分裂能力和合成硫酸粘多糖蛋白能力的变化。结果显示,虽用非洲血清细胞较易发生分裂,较难保持高分化状态,但未发现Mseleni病人血清与其他血清的明显不同,未能证实在Mseleni病人血清中存在损害关节软骨细胞的毒性物质。 Serum from the Mseleni patients in Africa and normal and non-infected normal sera were used instead of bovine serum to culture rabbit articular chondrocytes and human chondrocytes. The ability of cell division and the ability of synthesizing mucopolysaccharides were observed. The results showed that although sera from African countries were more likely to split, it was more difficult to maintain a well-differentiated state. However, no significant difference was found between serum from Mseleni patients and other sera, which did not confirm the presence of toxic substances that damaged articular chondrocytes in Mseleni’s serum.