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加《医学邮报》第15卷第26期(1979年)第16页报道多伦多消息:英国米德尔塞克斯中心医院的顾问医生米什威兹(J.J.Misiewicz)说,经证实,组织胺H_2受体拮抗剂甲氰咪胺对于治疗溃疡有效,但据最近双盲试验表明,此药在应用中有很大的局限性。经20次、共包括1,200例病人的双盲试验证实,应用甲氰咪胺治疗十二指肠溃疡,平均治愈率为77%,用安慰剂的对照组治愈率为44%。上述结果经内窥镜评定。甲氰咪胺每天剂量为0.8~2克。以上治疗结果证实,甲氰咪胺的疗效仅
Plus Medical Journal Vol. 15, No. 26 (1979) Page 16 REPORT Toronto News: JJ Misiewicz, consultant to Middlesex Central Hospital in the United Kingdom, said histamine H_2 The receptor antagonist cimetidine is effective in the treatment of ulcers, but recent double-blind trials have shown that the drug has great limitations in its application. After 20 rounds of double-blind trials involving 1,200 patients, the average cure rate was 77% with cacalamine in the treatment of duodenal ulcer and 44% with placebo. The above results were assessed by endoscopy. Cimetidine daily dose of 0.8 to 2 grams. The results of the above treatment confirmed that the efficacy of cimetidine only