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目的旨在通过收集整理2010-2014年期间天津市北辰区AEFI报告发生的数据,评价天津市北辰区AEFI信息报告管理系统监测数据指标及预防接种异常反应的发生率。方法通过中国AEFI信息管理系统收集2010-2014年天津市北辰区报告的AEFI个案数据和2010-2014年常规免疫监测数据采用描述流行病学方法进行分析。结果北辰区2010-2014年共报告AEFI案例268例次,总报告发生率21.45/十万剂次。AEFI报告发生率呈逐年增多的趋势。其中一般反应237例(占88.43%),异常反应29例(占10.82%),偶合症2例(占0.75%)。一岁及以下年龄组AEFI报告177例,占66.05%。疫苗接种与AEFI发生的间隔在0~1 d的报告例数为225例,占83.96%。百白破疫苗、麻疹疫苗的异常反应报告例数较多。结论不断提高AEFI监测质量,有利于更客观评价疫苗安全性,提高接种服务质量,更好地控制相关传染病的流行。
The purpose of this project is to collect data on the AEFI report of Beichen District in Tianjin during 2010-2014 and evaluate the monitoring data of AEFI information reporting management system in Beichen District of Tianjin and the incidence of abnormal response to vaccination. Methods AEFI case data collected from Beichen district of Tianjin in 2010-2014 and routine immunization surveillance data from 2010 to 2014 were collected by the China AEFI information management system and analyzed by descriptive epidemiological method. Results A total of 268 cases of AEFI were reported in Beichen District from 2010 to 2014, with a total reported incidence of 21.45 / 100 000 doses. The incidence of AEFI is increasing year by year. There were 237 cases (88.43%) in general reaction, 29 cases (10.82%) in abnormal reaction and 2 cases (0.75%) in couple. AEFI was reported in 177 patients (66.05%) in the age group of one and younger. The number of reported cases of vaccination with AEFI at 0-1 d was 225 (83.96%). Baitai broken vaccine, measles vaccine reported an abnormal response to the number of cases. Conclusions The continuous improvement of the quality of AEFI monitoring is conducive to more objective evaluation of vaccine safety, quality of vaccination services and better control of the prevalence of related infectious diseases.