Crove等对103例哮喘者的免疫学功能作了调查。其中87例给予皮内注射0.1毫升含有笰状菌(Aspergillus)、念珠菌、腮腺炎、旧结核菌素及链球菌的抗原物质,结果有8例迟发性过敏性皮肤试验阴性。8例中仅1例每日使用过2.5毫克的强的松龙,其余7例并未用过皮质激素。此资料与对照组(阳性98例,阴性1例)比较,有显著的差异(P<0.025)。这表明某些哮喘病人有细胞免疫机能低下的可能。 Crove et al investigated the immunological function of 103 asthmatics. Of these, 87 received intradermal injections of 0.1 ml of antigenic material containing Aspergillus, Candida, mumps, old tuberculin and streptococci. As a result, 8 patients with delayed-onset allergic skin tests were negative. Only one of eight patients had used 2.5 mg of prednisolone daily, and the remaining seven had no corticosteroids. This data and the control group (positive 98 cases, negative 1 case), there was a significant difference (P <0.025). This shows that some asthma patients have the possibility of cellular immune dysfunction.