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蛋白质组学从整体上,全面、动态、定量地分析正常及肿瘤标本中蛋白质种类和数量的改变,有助于阐明肿瘤相关蛋白质间的调控网络。卵巢癌是女性生殖器官恶性肿瘤中首位的致死性疾病,但卵巢位置隐匿,卵巢癌早期往往没有特异性症状,而现有的卵巢癌肿瘤标志物用于卵巢癌诊断价值有限,导致70%~75%的卵巢癌确诊时已是晚期,5年存活率低于30%,严重危害妇女健康。而蛋白质组学对上皮性卵巢癌具有广阔的应用前景,有助于卵巢癌的诊断、治疗等。
Proteomics Overall, comprehensive, dynamic and quantitative analysis of normal and tumor samples in the type and amount of protein changes help to clarify the tumor-related regulatory networks between proteins. Ovarian cancer is the first fatal disease in female genital malignancies, but the location of the ovary is hidden, the early symptoms of ovarian cancer often do not have specific, and the existing ovarian cancer tumor markers for the diagnosis of ovarian cancer is limited, resulting in 70% 75% of ovarian cancer is already diagnosed late, 5-year survival rate of less than 30%, seriously endangering women’s health. Proteomics on epithelial ovarian cancer has broad application prospects, contribute to the diagnosis and treatment of ovarian cancer.