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目的:对5种千斤拔的不同药用部位及3种千斤拔不同产地根中浸出物的含量进行测定,以期评价不同种的药材质量,为寻找新药源和新的药用部位提供一定的实验数据。方法:采用中国药典2005版浸出物测定方法。结果:水溶性浸出物中,蔓性千斤拔(湖北宜昌)的根、茎、叶中含量都最高。醇溶性浸出物中,根中大叶千斤拔(四川成都)含量最高;茎中球穗千斤拔(广西恭城)含量最高;叶中腺毛千斤拔(广西金秀三江)含量最高。挥发性醚类中,根中宽叶千斤拔(广西金秀三江)含量最高;茎中腺毛千斤拔(广西金秀三江)含量最高;叶中大叶千斤拔(四川成都)含量最高。3种千斤拔不同产地中浸出物的含量差别较大。结论:浸出物含量可作为控制千斤拔药材质量的重要指标之一;生态环境对千斤拔浸出物含量有明显影响;从资源的综合和可持续利用角度考虑,建议对球穗千斤拔、宽叶千斤拔、腺毛千斤拔进行药理研究,考察其能否作为新的替代资源,其茎、叶能否同等入药。
OBJECTIVE: To determine the content of different kinds of medicinal extracts in different root areas and the extracts of three species from different production areas in order to evaluate the quality of different species of medicinal materials and provide some experiments for finding new sources of drugs and new medicinal sites. data. Methods: The Chinese Pharmacopoeia 2005 version of the extract method was used. RESULTS: Among the water-soluble extracts, the highest content of roots, stems and leaves was found in Qianjinba (Yichang, Hubei Province). Among the alcohol-soluble extracts, the highest content was found in the roots of Daye Qianjinba (Chengdu, Sichuan); the content of stems and spikes in the stems was the highest (Gongcheng City, Guangxi Province); the content of the glands in the leaves was the highest among the Jinxiu Sanjiang. Among the volatile ethers, the content of the root broad-leaved caterpillar (Jinxiu Sanjiang, Guangxi) was the highest, the content of the glandular hairy caterpillar (Ganxiu Sanjiang, Guangxi) was the highest, and the content of the middle leaf Dajin Qiantu (Chengdu, Sichuan) was the highest. The content of leachables in the three different types of production areas varies greatly. Conclusion: The content of leachate can be used as one of the important indicators for controlling the quality of Qianjinba medicinal materials; the ecological environment has a significant impact on the content of leachable extracts from jackbow; considering the comprehensive and sustainable use of resources, it is recommended The pharmacological study of Qianjinbajin and Qianjinjinjiao was conducted to investigate whether it could be used as a new alternative resource and whether the stems and leaves could be equally used as medicine.