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青霉素引起的变态反应临床综合征差异很大,即刻反应包括过敏性、血管水肿、荨麻疹和某些斑丘疹。迟缓反应包括那些有明确免疫学基础的例如血清病样反应、溶血性贫血和急性间质性肾炎和其他尚不清楚的免疫性疾患,如某些中性白细胞减少症和由于氨(芋)青霉素引起的斑丘疹。即刻反应是IgE抗体介导的,而IgG抗体,至少是某些迟缓反应——例如,血清病和溶血性贫血的原因。
Allergic reactions caused by penicillin Clinical syndromes vary widely, and immediate reactions include allergies, angioedema, urticaria and some rash. Slow reactions include those with a clear immunological basis such as serum sickness-like reactions, hemolytic anemia and acute interstitial nephritis and other immunological disorders that are not yet clear, such as certain neutropenia and infections due to ammonia (taro) penicillin Cause rash. The immediate response is IgE antibody-mediated, whereas IgG antibodies are, at least some of the slow reactions - for example, the causes of serum sickness and hemolytic anemia.