在24届国际癫癎学术会上,由国际抗癫癎联盟提出的最新癫癎分类中,将负性肌阵挛列为一种癫癎发作类型。由于负性肌阵挛的临床表现往往不典型而且症状轻微,临床诊断有一定的困难。因此本文谨就其临床特点和病理生理机制作一概述。1概念和分类肌阵挛是指由中枢神经系统异常放电引起短暂 In the 24th International Conference on Epilepsy, the most recent classification of epilepsy proposed by the International League Against Epilepsy is to list negative myoclonus as a type of epileptic seizure. As the clinical manifestations of negative myoclonus are often not typical and mild symptoms, clinical diagnosis has some difficulties. Therefore, this article would like to give an overview of its clinical features and pathophysiological mechanisms. 1 concept and classification Myoclonus refers to the CNS caused by abnormal discharge transient