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目的:分析瑞芬太尼复合麻醉对小儿眼科手术患者的麻醉疗效及安全性。方法:选取2014年1—10月间行眼科手术患儿64例,随机分为观察组和对照组(每组32例);观察组患者均给予瑞芬太尼复合丙泊酚全身麻醉手术,对照组患者均给予异氟醚吸入全身麻醉手术,比较两组患者给药后的麻醉效果和安全性。结果:观察组患者给药麻醉后在气管插管后(T_3)、手术开始时(T_4)及手术结束时(T_5)的HR(心率)、MAP(平均动脉压)值均明显低于对照组(P<0.05);观察组患者拔管时间在5,15及30 min后的Ramsay评分值和Riker躁动评分值及FLACC疼痛评分值均显著低于对照组(P<0.05)。结论:采用瑞芬太尼复合丙泊酚全身麻醉对小儿眼科手术患者全身麻醉,具有明显的镇静止痛疗效,能有效地维持和稳定患儿术中血流动力学参数,促使患儿术后能快速苏醒。
Objective: To analyze the anesthesia efficacy and safety of remifentanil anesthesia in pediatric ophthalmic surgery patients. Methods: Sixty-four children underwent ophthalmic surgery from January to October 2014 were randomly divided into observation group and control group (32 in each group). All patients in observation group were given remifentanil combined with propofol for general anesthesia, Control group patients were given isoflurane inhalation anesthesia surgery, compared two groups of patients after administration of anesthesia and safety. Results: HR (heart rate) and MAP (mean arterial pressure) in the observation group after anesthesia were significantly lower than those in the control group after T 3, T 4 and T 5, (P <0.05). The Ramsay score, Riker agitation score and FLACC pain score of the observation group at extubation time 5, 15 and 30 min were significantly lower than those of the control group (P <0.05). Conclusion: Remifentanil and propofol combined with general anesthesia for pediatric ophthalmic surgery in patients with general anesthesia, with significant analgesic effect of sedation, can effectively maintain and stabilize the hemodynamic parameters in children with children to promote postoperative Wake up quickly.