三氯乙烯(TCE)是一种常用的有机溶剂,广泛应用于电镀或五金工件的去污、不锈钢制品的清洁剂、印刷电路板清洗等方面。TCE可以通过呼吸系统和皮肤吸收。近年来广东等地TCE接触者常发生三氯乙烯药疹样皮炎,出现严重皮肤损害和肝肾功能损害甚至死亡。由于只有少数TCE接触者发病,而且发病与所接触TCE的浓度无明显关系,故有研究者认为该病可能是一种变态反应性疾病。因此本文对TCE引起变态反应及其对免疫系统的影响进行综述。 Trichlorethylene (TCE) is a commonly used organic solvent, widely used in electroplating or metal parts decontamination, stainless steel cleaner, PCB cleaning and so on. TCE can be absorbed through the respiratory system and skin. TCE contacts in Guangdong and other places in recent years often occur trichlorethylene edematous dermatitis, severe skin damage and liver and kidney dysfunction or even death. As only a small number of TCE contacts and incidence of exposure to TCE concentration was not significantly correlated, so some researchers think the disease may be an allergic disease. Therefore, this article reviews the effects of TCE on allergic reactions and their effects on the immune system.