宿主对病原体的易感性是受遗传基因控制的。近年来 ,各国学者通过抗性动物品系的筛选、近交系动物杂交分析、遗传系谱分析、标志基因连锁分析、等位基因分析、基因突变分析、转基因小鼠模型和基因剔除小鼠模型等方法和技术 ,对宿主的 ,特别是小鼠和人的抗感染相关基因进行了研 Host susceptibility to pathogens is genetically controlled. In recent years, scholars from all over the world have screened resistant strains of animals, inbred animals hybridization analysis, genetic pedigree analysis, marker gene linkage analysis, allele analysis, gene mutation analysis, transgenic mouse models and gene knockout mouse models Methods and techniques, the host, especially mice and human anti-infective-related genes were studied