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目的探讨ATAb与反复自发性流产之间的关系。方法应用ELISA方法检测了186例自发性流产患者血清中ATAb,并以56例正常育龄妇女作为对照。结果反复自发性流产患者血清中的ATAb阳性率为1882%,而正常对照组的阳性率为197%(P<001)。ATAb阳性率随流产次数的增加而增加(P<005),但与流产时孕期之间无明显关系。结论弓形体感染与反复自发性流产密切相关,尤其多次流产的患者检测ATAb更为重要。
Objective To explore the relationship between ATAb and recurrent spontaneous abortion. Methods ATAb was detected in serum of 186 patients with spontaneous abortion by ELISA, and 56 healthy women of childbearing age were taken as control. Results The positive rate of ATAb in patients with recurrent spontaneous abortion was 1882%, while the positive rate in normal control group was 197% (P0.01). The positive rate of ATAb increased with the increase of the number of abortion (P <005), but no significant relationship with the pregnancy during abortion. Conclusion Toxoplasmosis is closely related to recurrent spontaneous abortion, especially in patients with multiple abortion.