Sjgren综合征患者的角膜结膜干燥症及口腔干燥症系泪腺、副泪腺及唾液腺长期有单核细胞浸润,最终破坏腺体的结构,使分泌功能减低,弓f起减少或无泪液及唾液所致。此综合征在临床上有两种类型:(1)原发型:仅有角膜结膜干燥及口腔干燥症。(2)继发型:除干燥症外合并有其他结缔组织的病变。最近研究提示二者在遗传学,免疫学,血清学及临床方面均有差别。由于对症治疗常失败,早期病例其腺体结构尚可恢复,因而需要探索有效的治疗及预防。一些自身免疫病用类固醇全身治疗有效果,眼部症状亦有所改善。基于此实践,作者用中等剂量泼尼松问日服用,治疗原发性sj(?)gren综合征7例女性患者,年龄为21～53岁,平均42岁。以往均未接受任何全身治疗。不合并糖尿病、高血压症 Sjogren’s syndrome in patients with corneal conjunctival xerophthalmia and xerostomia, lacrimal gland, accessory lacrimal gland and salivary glands long mononuclear cell infiltration, the final destruction of the structure of the gland, so that secretory function decreased bow f from less or no tears and saliva Due. This syndrome in the clinical there are two types: (1) the original type: only the corneal conjunctival dry and xerostomia. (2) secondary type: In addition to xerosis combined with other connective tissue lesions. Recent research suggests that there is a difference in genetics, immunology, serology and clinical aspects. As symptomatic treatment often fails, early glandular structure can still be restored, and therefore need to explore effective treatment and prevention. Some autoimmune diseases have systemic effects with steroids and eye symptoms have also been improved. Based on this practice, the authors treated with moderate-dose prednisone on the day, the treatment of primary sj? Gren syndrome in 7 women, aged 21 to 53 years, mean 42 years. None of them had received any systemic treatment in the past. Not combined with diabetes, hypertension