目的:研究分析喜炎平注射液联用抗菌药物和抗菌药物单一用药治疗小儿急性上呼吸道感染的疗效及其对炎性指标的影响。方法:选取急性上呼吸道感染患儿80例,随机分为对照组和治疗组,每组40例。对照组予抗菌药物静脉滴注,治疗组予喜炎平注射液+抗菌药物联合治疗,疗程均为3~7 d。治疗后观察两组的临床疗效,检测两组患儿治疗前后白细胞计数(WBC)和超敏C-反应蛋白(hs-CRP)水平,并进行对比分析。结果:治疗3 d后对照组和治疗组痊愈率分别为17.5%、40.0%,总有效率分别为80.0%、100%;两组总有效率比较,差异有统计学意义(P<0.05)。治疗组患儿发热、咳嗽、咽痛等症状的消失比例显著高于对照组,主要症状消失时间亦显著缩短;与治疗前比较,治疗后两组WBC、hs-CRP水平均有显著改善,差异均有统计学意义(P<0.05);且治疗组治疗后WBC、hs-CRP水平均较对照组有显著改善(P<0.05)。结论:喜炎平注射液联用抗菌药物用于治疗小儿急性上呼吸道感染疗效确切,起效迅速。 Objective: To study the effect of Xiyanping injection combined with antimicrobial agents and antimicrobial agents on the treatment of acute upper respiratory tract infection in children and its influence on inflammatory indexes. Methods: Eighty children with acute upper respiratory tract infection were randomly divided into control group and treatment group, 40 cases in each group. The control group was treated with intravenous infusion of antibacterial drugs, and the treatment group was treated with Xiyanping injection plus antibacterial drugs for 3 ~ 7 days. After treatment, the clinical efficacy was observed in both groups. The WBC and hs-CRP levels in both groups were measured and compared before and after treatment. Results: After 3 days of treatment, the cure rates of the control group and the treatment group were 17.5% and 40.0%, respectively. The total effective rates were 80.0% and 100% respectively. There was significant difference between the two groups in total effective rate (P <0.05). The disappearance rate of fever, cough, sore throat and other symptoms in the treatment group was significantly higher than that in the control group, and the disappearance time of the main symptoms was also significantly shortened. Compared with those before treatment, the WBC and hs-CRP levels were significantly improved in both groups (P <0.05). The levels of WBC and hs-CRP in the treatment group were significantly improved as compared with those in the control group (P <0.05). Conclusion: Xiyanping injection combined with antimicrobial drugs for the treatment of acute upper respiratory tract infection in children with exact effect, rapid onset.