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目的:观察雾化吸入“复方三拗液”治疗慢性阻塞性肺疾病(慢阻肺)的临床疗效。方法:以“复方三拗液”雾化吸入方式给药治疗50例慢阻肺患者(治疗组),同时用银黄平喘气雾剂及常规西药(庆大霉素、糜蛋白酶)雾化吸入治疗各30例慢阻肺患者作对照(对照A组和对照B组)。结果:治疗组、对照A组和对照B组的总有效率分别为96.0%、80.0%和76.6%,治疗组总有效率明显高于对照A组及对照B组(P<0.05及P<0.01)。治疗组患者在临床症状改善的同时,动脉血气分析、血纤维蛋白原、红细胞压积及肺通气功能等指标亦得到改善。结论:“复方三拗液”雾化吸入法治疗慢阻肺疗效肯定,值得深入研究和推广应用。
Objective: To observe the clinical effect of inhalation “compound Sanan liquid” on chronic obstructive pulmonary disease (COPD). Methods: Fifty patients with chronic obstructive pulmonary disease (treated group) were treated with “Fufang Sanan Liquid” aerosol inhalation. At the same time, the patients were treated with aerosol inhalation of Yinhuang Pingchuan and conventional western medicine (gentamicin and chymotrypsin) 30 cases of COPD patients as control (control group A and control group B). Results: The total effective rates of the treatment group, control group A and control group B were 96.0%, 80.0% and 76.6% respectively. The total effective rate in the treatment group was significantly higher than that in the control group A and the control group B <0.05 and P <0.01). In the treatment group, the improvement of clinical symptoms, arterial blood gas analysis, fibrinogen, hematocrit and pulmonary ventilation and other indicators also improved. Conclusion: “Fufang Sanan Liquid” aerosol inhalation therapy is effective in treating chronic obstructive pulmonary disease, which deserves further study and popularization and application.