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目的验证伽玛刀治疗脑转移瘤的有效性和安全性。方法脑转移瘤患者38例(70个病灶)先进行常规全脑放疗后采用杭州华源伽玛医疗设备投资有限公司生产的WB-SRS260伽玛刀立体定向适形照射转移灶。肿瘤边缘剂量2.5~5Gy/次,1次/d,5次/周,计划靶区边缘(50%的等剂量线处)总剂量32~50 Gy。结果完全缓解(CR)15例(39.5%),部分缓解(PR)19例(50%),肿瘤好转(MR)1例(2.6%),稳定(SD)3个(7.9%),有效率为89.5%。大多数未出现严重不良反应(79%)。结论伽玛刀治疗脑转移瘤安全有效。
Objective To verify the effectiveness and safety of gamma knife in the treatment of brain metastases. Methods Thirty-eight patients with brain metastases (70 lesions) were treated with WB-SRS260 gamma knife stereotactic radiation irradiation produced by Hangzhou Huayuan Gamma Medical Equipment Investment Co., Ltd. after routine whole-brain radiotherapy. Tumor marginal dose of 2.5 ~ 5Gy / time, 1 / d, 5 times / week, the planned target edge (50% of the dose line) at a total dose of 32 ~ 50 Gy. Results The complete response (CR) was achieved in 15 cases (39.5%), partial response (PR) in 19 cases (50%), tumor revascularization (MR) in 1 case 89.5%. Most did not show serious adverse reactions (79%). Conclusion Gamma knife treatment of brain metastases safe and effective.