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目的观察整蛋白型肠内营养液治疗重症急性胰腺炎(SAP)的疗效。方法58例SAP患者按照常规SAP治疗方案治疗,采用胃镜辅助置入鼻肠管后行空肠喂养,分别滴入肠内营养混悬液(整蛋白组29例)和肠内营养粉剂(要素组29例),观察两组治疗1周后的ALT、C反应蛋白、前白蛋白和白蛋白等营养指标变化及患者胃肠道耐受度、腹泻发生率、并发感染率和28d病死率等。结果两组治疗1周后相关营养指标值均相仿(P>0.05)。两组患者胃肠道耐受度、腹泻发生率、并发感染率、住院天数以及28d病死率均相仿(P>0.05)。结论整蛋白型肠内营养液具有良好的肠道耐受性,效果好。
Objective To observe the effect of whole protein enteral nutrition in the treatment of severe acute pancreatitis (SAP). Methods Fifty-eight patients with SAP underwent conventional SAP treatment. Gastroscope-assisted naso-jejunal feeding was used to perform jejunal feeding. Enteral nutrition suspensions (whole protein group, n = 29) and enteral nutrition powder (n = 29) ). The changes of nutritional indexes such as ALT, C-reactive protein, prealbumin and albumin and the gastrointestinal tolerance, the incidence of diarrhea, the rate of concurrent infection and the mortality of 28d were observed after treatment for one week. Results The nutritional value of the two groups after 1 week of treatment were similar (P> 0.05). The gastrointestinal tolerance, the incidence of diarrhea, the rate of concurrent infection, days of hospitalization and mortality at 28 days in both groups were similar (P> 0.05). Conclusion The whole protein enteral nutrition solution has good intestinal tolerance and good effect.