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目的评价改良颅内外血管吻合术治疗缺血性脑血管病的疗效。方法对5例颈动脉闭塞患者行改良颅内外血管吻合术,分析术前、术后的脑血流动力学改变及临床症状,并进行7～12个月的随访。结果5例患者临床症状有所改善,在随访期间无卒中发生,单光子发射电子计算机断层扫描(SPECT)行局部脑血流量(rCBF)测定,显示脑血流量较术前有所增加。结论颅内外血管吻合术可有效地改善脑局部血流动力学状况及临床症状,预防完全性卒中的发生,远期疗效尚需进一步证实。
Objective To evaluate the efficacy of modified intracranial and extravascular vascular anastomosis in the treatment of ischemic cerebrovascular disease. Methods Five patients with carotid artery occlusion underwent modified intracranial and extracranial vascular anastomosis. The changes of hemodynamics and clinical symptoms before and after operation were analyzed and followed up for 7-12 months. Results The clinical symptoms were improved in 5 patients. No stroke occurred during the follow - up. SPECT followed by local cerebral blood flow (rCBF) showed that the cerebral blood flow increased. Conclusion Intracranial extravascular vascular anastomosis can effectively improve the local hemodynamic status and clinical symptoms, prevent the occurrence of complete stroke, the long-term efficacy needs further confirmation.