该文简要介绍了近年来国内外对壳聚糖作为基因载体的转染机制、结构修饰的认识及对转染效率影响因素的分析和优化;并主要介绍了壳聚糖具有基因活化作用的最新研究概况。壳聚糖基因载体是一种新型基因载体,具有广阔的发展前景。 In this paper, the mechanism of transfection of chitosan as a gene carrier at home and abroad is briefly introduced. The understanding of the mechanism of transfection, the analysis and optimization of the transfection efficiency factors are introduced briefly. The most recent work on the gene activation of chitosan Research Overview. Chitosan gene vector is a new type of gene carrier, which has broad prospects for development.