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背景与目的:微波固化治疗口底癌在保护口腔功能方面的研究较少。本研究旨在探讨微波固化治疗过程中的两种特殊处理方式的意义及出血的预防。方法:回顾性分析经微波固化治疗的96例口腔癌病例,比较清除的固化组织病理学检查阴性组和阳性组生存曲线和复发率,比较手术切缘组织病理学阴性组和阳性组的生存曲线和复发率,分析微波固化的并发症及其防治。结果:固化组织病理学检查阴性组和阳性组生存曲线的差异无统计学意义(Log-rank=0.70,P=0.4033),原发灶、继发灶和复发灶不明者复发率的差异也无统计学意义(χ2=1.650,0.837,0.003;P=0.684,0.360,0.959);手术切缘组织病理学阴性组的总体生存时间高于阳性组(Log-rank=6.08,P=0.0136),但复发率的差异则无统计学意义(χ2=0.327,P=0.567);96例患者的总体并发症发生率为9.6%,都是可以接受的,微波固化组织清除组的出血发生率较微波固化组织未清除组的低(P=0.013)。结论:舌动脉结扎、固化组织清除、创缘缝扎碘仿纱压迫是防止术后出血的有效方法,但微波固化组织的病理学检查结果对预后没有预测作用。术中宜确保足够的固化治疗范围。微波固化治疗口底癌时并发症少且较轻微。
BACKGROUND & OBJECTIVE: There is little research on oral cancer curing oral mucosa by microwave curing. The purpose of this study was to explore the significance of two special treatment modalities and the prevention of bleeding in the course of microwave curing. Methods: 96 cases of oral cancer treated by microwave curing were retrospectively analyzed. The survival curves and recurrence rates of the negative group and the positive group were compared. The survival curves of the negative group and the positive group were compared And recurrence rate, analysis of microwave curing complications and prevention. Results: There was no significant difference in survival curves between the negative group and the positive group (Log-rank = 0.70, P = 0.4033). There was no difference in the recurrence rate between the primary tumor, the secondary tumor and the recurrence focus Statistical significance (χ2 = 1.650,0.837,0.003; P = 0.684,0.360,0.959); Survival margin histopathology negative group overall survival time was higher than the positive group (Log-rank = 6.08, P = 0.0136), but There was no significant difference in recurrence rate (χ2 = 0.327, P = 0.567). The overall complication rate in 96 patients was 9.6%, which was acceptable. The incidence of hemorrhage in microwave-cured tissue-removed group was higher than that in microwave- Tissues were not cleared in the low group (P = 0.013). CONCLUSION: Tongue artery ligation, solidified tissue removal and wound healing with iodoform gauze are effective methods to prevent postoperative bleeding. However, the pathological results of microwave solidified tissue have no predictive value on prognosis. Intraoperative should ensure adequate cure treatment. Microwave curing of mouth cancer with less complications and less.