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为探讨侯氏黑散对缺血性脑病的疗效机理,实验观察了该药对兔的心、肝、脑、肺、肾组织匀浆液脂质过氧化物的影响。结果表明:侯氏黑散可降低组织匀浆液脂质氧化物的含量,与生理盐水组比较有显著差异,提示本品有较强抑制脂质过氧化反应的作用,故可减轻组织缺血造成的损伤,这可能是其治疗缺血性脑病的机理之一。
In order to investigate the therapeutic mechanism of Houshiheishan on ischemic encephalopathy, the effects of the drug on lipid peroxides in rabbit hearts, liver, brain, lung, and kidney homogenate were observed experimentally. The results showed that: Hou’s black powder can reduce the content of lipid oxides in the tissue homogenate, and there is a significant difference compared with the saline group, suggesting that this product has a stronger effect of inhibiting lipid peroxidation, so it can reduce the tissue ischemia The injury, which may be one of the mechanisms of its treatment of ischemic encephalopathy.