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目的研究妊娠期细菌性阴道炎不同疗程乳酸杆菌治疗的效果比较。方法对2012年1～5月在本院产检的妊娠期妇女共122例,常规进行细菌性阴道炎(BV)测定,BV阳性者用乳酸杆菌治疗一疗程后复查,仍为阳性者予第二疗程治疗,并对转阴率及孕产妇并发症进行比较。结果双疗程治疗后转阴率明显高于单疗程患者(P<0.01);双疗程治疗组胎膜早破、早产的发生率均明显高于单疗程治疗组(P<0.005,P<0.01);两组产褥感染及产后出血的发生率差异无统计学意义(P>0.05)。结论对于BV阳性的患者,经治疗后不论BV是否仍然持续阳性,建议只给予单疗程治疗,重复疗程治疗不能降低妊娠期相关并发症。
Objective To study the effect of lactobacilli treated by different courses of bacterial vaginosis during pregnancy. Methods A total of 122 pregnant women during the period from January to May in 2012 were enrolled in this study. Bacterial vaginitis (BV) was routinely measured. Patients with BV positive were treated with Lactobacillus for one course of treatment and then were still positive Course of treatment, and to negative rate and maternal complications were compared. Results The rate of negative conversion after double treatment was significantly higher than that of single treatment (P <0.01). The incidence of premature rupture of membranes and premature labor were significantly higher in double treatment group than in single treatment group (P <0.005, P <0.01) There was no significant difference between the two groups in the incidence of puerperal infection and postpartum hemorrhage (P> 0.05). CONCLUSIONS: For BV-positive patients, regardless of whether BV remains positive after treatment, it is recommended that only a single course of treatment be given and that repeated course of treatment does not reduce pregnancy-related complications.