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目的利用聚合酶链反应(PCR)鉴别诊断新生儿性传播性结膜炎并因病施治。方法对114例双眼急性结膜炎的新生儿进行淋球菌、沙眼衣原体、解脲脲原体PCR检查,并根据其病因采取相应的治疗。结果86例诊断为性传播性结膜炎,其中感染淋球菌44例(5116%),沙眼衣原体22例(2558%),解脲脲原体5例(581%);合并感染淋球菌和沙眼衣原体10例(1163%),淋球菌和解脲脲原体4例(465%),沙眼衣原体和解脲脲原体1例(116%)。86例全部治愈。结论PCR可作为新生儿性传播性结膜炎的新诊断方法,并应根据病因作相应的治疗
Objective To identify and diagnose neonatal sexually transmitted conjunctivitis by polymerase chain reaction (PCR). Methods One hundred and fourteen newborns with acute conjunctivitis of both eyes were diagnosed by Neisseria gonorrhoeae, Chlamydia trachomatis and Ureaplasma urealyticum, and the corresponding treatment was taken according to their etiology. Results 86 cases were diagnosed as sexually transmissible conjunctivitis. Among them, 44 cases (5116%) were infected with Neisseria gonorrhoeae, 22 cases (2558%) were infected with Chlamydia trachomatis, and 5 cases were Ureaplasma urealyticum (581%). Neisseria gonorrhoeae and Chlamydia trachomatis 10 (1163%), 4 (465%) Neisseria gonorrhoeae and Ureaplasma urealyticum, 1 (116%) Chlamydia trachomatis and Ureaplasma urealyticum. 86 cases were completely cured. Conclusion PCR can be used as a new diagnostic method of neonatal sexually transmitted conjunctivitis, and should be based on the cause of the corresponding treatment