论文部分内容阅读
近年来,已证实产毒大肠杆菌(ETEC)是引起人类急性腹泻的重要病原,也是发展中国家婴幼儿腹泻的主要病原。ETEC致病机理研究的较为清楚,主要是细菌通过污染食物和水,经口进入肠道,细菌借助定居因子定居于近端小肠粘膜上,并产生肠毒素(外毒素),引起分泌亢进,而致水样腹泻。我们于1989年3-10月对济南市历城区近郊202例腹亢患者做了病原学监测(历城区是山东省的腹泻监测点)。在检出的72株病原菌中,有56株是ETEC,而且主要集中在区驻地洪
In recent years, it has been proven that toxin-producing Escherichia coli (ETEC) is an important etiological agent causing acute diarrhea in humans and is also a major cause of diarrhea in infants and young children in developing countries. The pathogenesis of ETEC is relatively clear. The main reason is that bacteria enter the intestine through contaminated food and water, colonize the proximal small intestinal mucosa by colonizing factors and produce enterotoxins (exotoxins) Cause watery diarrhea. In March-October 1989, we conducted etiological surveillance on 202 cases of hyperparathyroidism in the suburbs of Licheng District, Jinan City (Licheng District is a diarrhea monitoring site in Shandong Province). Of the 72 pathogenic bacteria detected, 56 were ETECs and were mainly concentrated in the district resident floods