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目的观察丁苯酞软胶囊联合依达拉奉治疗急性脑梗死的临床疗效。方法入选60例急性脑梗死患者,随机分为观察组30例和对照组30例,以血栓通、奥扎格雷钠和阿司匹林为基础治疗,观察组在基础治疗上予丁苯酞软胶囊0.2g,3次/d口服,依达拉奉30mg,2次/d静脉滴注,疗程2周。对照组在基础治疗上予依达拉奉30mg,2次/d静脉滴注,疗程2周。对比临床疗效和神经功能缺损程度评分。结果两组神经功能缺损评分均有所改善,但观察组疗效明显优于对照组(P<0.05),差异有统计学意义。结论丁苯酞软胶囊联合依达拉奉治疗急性脑梗死疗效满意,值得临床广泛应用。
Objective To observe the clinical efficacy of butylphthalide soft capsule combined with edaravone in the treatment of acute cerebral infarction. Methods Sixty patients with acute cerebral infarction were enrolled and randomly divided into observation group (30 cases) and control group (30 cases). Xueshuantong, ozagrel and aspirin were used as the basis for the observation group. Butylphthalide soft capsule 0.2 g , 3 times / d orally, edaravone 30mg, 2 times / d intravenous infusion, treatment for 2 weeks. The control group was given edaravone 30mg on the basis of treatment, 2 times / d intravenous infusion for 2 weeks. Comparison of clinical efficacy and neurological deficit score. Results The scores of neurological deficit in both groups were improved, but the curative effect in the observation group was better than that in the control group (P <0.05). The difference was statistically significant. Conclusion Butylphthalide soft capsule combined with edaravone in the treatment of acute cerebral infarction with satisfactory results, it is widely used in clinical.