目的：探讨失代偿期肝硬化患者低钠血症与低蛋白血症的关系。方法：对５４例失代偿期肝硬化患者的８２份血标本进行的血电解质及血浆白蛋白测定结果进行分析。结果：失代偿期肝硬化患者低钠血症的发生率为４６％。血浆白蛋白的平均值在血钠正常组（Ｎａ＋＞１３５ｍｍｏｌ／Ｌ）为２６３ｇ／Ｌ；在轻度低钠组（Ｎａ＋１３１～１３５ｍｍｏｌ／Ｌ）为２４１ｇ／Ｌ；在中度低钠组（１２６～１３０ｍｍｏｌ／Ｌ）为２２１８ｇ／Ｌ；在重度低钠组（Ｎａ＋＜１２５ｍｍｏｌ／Ｌ）为１８６８ｇ／Ｌ。血浆钠降低程度与低蛋白血症程度呈正相关ｒ＝０６９（Ｐ＜０００１）。结论：低蛋白血症是导致失代偿期肝硬化患者低钠血症的一个重要原因。 Objective: To investigate the relationship between hyponatremia and hypoalbuminemia in patients with decompensated cirrhosis. Methods: The blood electrolytes and plasma albumin in 82 blood samples from 54 patients with decompensated cirrhosis were analyzed. Results: The incidence of hyponatremia in decompensated cirrhosis patients was 46%. The mean value of plasma albumin was 263g / L in normal serum sodium group (Na> 135mmol / L), 241g / L in mild low sodium group (Na + 131 ~ 135mmol / L) Group (126 ~ 130mmol / L) was 2218g / L; in severe hyponatremia group (Na ± 125mmol / L) was 1868g / L. There was a positive correlation between the degree of plasma sodium reduction and the degree of hypoproteinemia (r = 0.69, P <0001). Conclusion: Hypoproteinemia is an important cause of hyponatremia in patients with decompensated cirrhosis.