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体内细胞受到物理(射线等)、化学(致癌剂)及生物因子(病毒、霉菌毒素等)的作用,影响细胞核内 DNA 上基因突变,导致整个细胞生物性质发生变化:失去正常细胞所具有的接触抑制,体外培养多层增殖,细胞膜通透性增高,对外源凝集素的凝集力较相应正常细胞强等。体外用细胞免疫及体液免疫的方法测得正常细胞所不具有的新抗原。人类肿瘤细胞是否也与动物肿瘤一样,具有特异性抗原,到目前尚未完全确定。然而,伯基氏淋巴瘤、
The cells in the body are affected by physics (rays, etc.), chemicals (carcinogens), and biological factors (viruses, mycotoxins, etc.) and affect DNA mutations in the nucleus, leading to changes in the biological properties of the entire cell: loss of contact with normal cells. Inhibition, multi-layer proliferation in vitro, increased cell membrane permeability, and agglutination of exogenous lectin were stronger than that of normal cells. In vitro, cell antigens and humoral immunity were used to measure new antigens that were not found in normal cells. Whether human tumor cells also have the same specific antigen as animal tumors has not yet been fully established. However, Burkitt’s lymphoma,