患者男,48岁。于1982年10月4日第1次来我科就诊,主因23年来,双手足关节肿痛,开始于第一跖趾关节,以后逐渐扩展至指、趾关节和右肘关节。13年前,常因精神紧张,过度劳累而诱发红、肿、热痛和活动受限;偶伴全身冷热不适。每年至少诱发1～2次。开始考虑“类风湿性关节炎”, Male patient, 48 years old. On the first visit to our department on October 4, 1982, the main cause of swelling and pain of both hands and feet began in the first metatarsophalangeal joint for 23 years and gradually expanded to the fingers, toe joints and right elbow. Thirteen years ago, often due to mental stress, overwork and induced redness, swelling, heat pain and limited activity; even with the whole body hot and cold discomfort. Induced at least 1 or 2 times a year. Began to consider “rheumatoid arthritis”