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盐酸木防已碱(TrL)有镇痛、解热作用,不产生身体依赖。本文报告TrL的抗炎作用。 1.抑制多种致炎剂产生的足跖肿胀:于大鼠足跖皮下分别注射蛋清、2.5％甲醛0.1ml或1％角叉菜胶)。15ml致炎,用毛细管放大测量法测量各组大鼠致炎前后足跖体积的变化。设生理盐水和消炎痛组作对照。结果,TLr20～40mg/kg ip或400mg/kg ig对各种致炎剂所致肿胀都有明显抑制作用,摘除
Tranylalanine hydrochloride (TrL) has analgesic and antipyretic effects and does not produce physical dependence. This article reports the anti-inflammatory effects of TrL. 1. Inhibition of paw engorgement caused by various inflammatory agents: Egg white, 2.5% formaldehyde 0.1 ml or 1% carrageenan were injected subcutaneously into the rat squamous pad. Fifteen ml of inflammation was induced. Changes in the volume of paws were measured before and after inflammation in each group of rats by capillary amplification. Set saline and indomethacin groups as controls. As a result, TLr of 20-40 mg/kg ip or 400 mg/kg ig significantly inhibited the swelling caused by various inflammatory agents.