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目的:探讨进展期胃癌患者围手术期腹腔热灌注化疗的安全性。方法:回顾性分析2013年5月至2016年1月我院收治的、经病理学确诊的、可根治性切除的进展期胃癌患者70例,采用随机数字表法将患者分为两组:治疗组30例和对照组40例。治疗组行腹腔镜下D2标准胃癌根治术+腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy(HIPEC)),对照组仅行腹腔镜下D2标准胃癌根治术。观察围手术期两组毒副反应及并发症。结果:回顾性分析2013年5月至2016年1月我院收治的、经病理学确诊的、可根治性切除的进展期胃癌患者70例,采用随机数字表法将患者分为两组:治疗组30例和对照组40例。治疗组行腹腔镜下D2标准胃癌根治术+腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy(HIPEC)),对照组仅行腹腔镜下D2标准胃癌根治术。观察围手术期两组毒副反应及并发症。结论:进展期胃癌患者行腹腔镜下D2标准胃癌根治术+HIPEC,在围手术期内,不增加感染机会及术后并发症的发生率、不延长术后恢复时间,是一项安全可靠的综合性治疗手段,值得临床推广。
Objective: To investigate the safety of peritoneal thermochemotherapy in patients with advanced gastric cancer. Methods: A retrospective analysis of 70 patients with advanced gastric cancer who underwent radical resection in our hospital from May 2013 to January 2016 was performed. Patients were divided into two groups according to random number table: treatment Group of 30 cases and control group of 40 cases. The patients in the treatment group underwent laparoscopic D2 standard radical gastrectomy plus hyperthermic intraperitoneal chemotherapy (HIPEC). The control group received laparoscopic D2 standard radical gastrectomy only. Perioperative observation of two groups of side effects and complications. Results: A retrospective analysis of 70 cases of advanced gastric cancer with pathologically confirmed radical resection in our hospital from May 2013 to January 2016 was performed. The patients were divided into two groups according to the random number table: treatment Group of 30 cases and control group of 40 cases. The patients in the treatment group underwent laparoscopic D2 standard radical gastrectomy plus hyperthermic intraperitoneal chemotherapy (HIPEC). The control group received laparoscopic D2 standard radical gastrectomy only. Perioperative observation of two groups of side effects and complications. Conclusions: Laparoscopic D2 standard gastric cancer radical mastectomy + HIPEC is a safe and reliable method for patients with advanced gastric cancer without increasing the chances of infection and the incidence of postoperative complications during the perioperative period, without prolonging the recovery time Comprehensive treatment, it is worth clinical promotion.