论文部分内容阅读
本文观察了急性白血病患者ＣＳＦ－ＦＮ和Ｆ含量，结果ＣＮＳＬ患者ＣＳＦ－ＦＮ和Ｆ含量全部升高，与对照组及无ＣＮＳＬ组比较有极显著性差异（Ｐ＜０．０１）。１０例ＣＮＳＬ患者治疗后８例缓解的ＣＳＦ－ＦＮ和Ｆ明显下降；一例虽缓解但下降不明显，半月后复发。另一例病情恶化，ＣＳＦ－ＦＮ和Ｆ反较治疗前升高。无ＣＮＳＬ组３０例患者９例ＣＳＦ－ＦＮ增高，８／２３例ＣＳＦ－Ｆ增高，其中二项同时增高的有７例，随访１５—８０天，有５例确诊为ＣＮＳＬ。本文提示ＣＮＳＬ确诊前ＣＮＳ已受到白血病细胞的浸润；ＣＳＦ－ＦＮ和Ｆ是诊断ＣＮＳＬ的敏感指标，有助于ＣＮＳＬ的早期诊断和疗效监测。
In this study, the CSF-FN and F levels in patients with acute leukemia were observed. As a result, CSF-FN and F levels in CNSL patients were all increased, and there was a significant difference between the control group and the non-CNSL group (P<0.01). The CSF-FN and F remission in 8 cases of CNSL patients after treatment were significantly decreased after treatment; in one case, the CSF-FN and F did not decrease significantly, but relapsed after half a month. In another condition, the CSF-FN and F were higher than before treatment. In the non-CNSL group, 9 cases of CSF-FN increased in 8 cases, and 8/23 cases of CSF-F increased. Among them, 7 cases of both cases increased at the same time. In the follow-up of 15-80 days, 5 cases were diagnosed as CNSL. This article suggests that CNS has been infiltrated by leukemia cells before diagnosis of CNSL; CSF-FN and F are sensitive indicators for the diagnosis of CNSL, which contributes to the early diagnosis and efficacy monitoring of CNSL.