Exploration of Mutation and DNA Methylation of Polo-Like Kinase 1 (PLK1) in Colorectal Cancer

来源 :病理学期刊(英文) | 被引量 : 0次 | 上传用户：yahved

【摘要】

：

Polo-like kinase 1 (PLK1) is a serine/threonine kinase that plays critical roles in cell cycling and DNA damage response. Overexpression of PLK1 is associated w

【作者】

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Wayne Ng Joo-Shik Shin Bin Wan

【机构】

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DisciplineofPathology,CentreforOncologyEducationandResearchTranslation,SouthWesternSydneyClinicalSch

【出处】

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病理学期刊(英文)

【发表日期】

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2017年3期

【关键词】

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PLK1 CRC MUTATION DNA METHYLATION SEQUENCING PLK1 CRC Mutation DNA Methylation S

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Polo-like kinase 1 (PLK1) is a serine/threonine kinase that plays critical roles in cell cycling and DNA damage response. Overexpression of PLK1 is associated with the poorer prognosis of cancers, including colorectal cancer (CRC). Although the downstream

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Exploration of Mutation and DNA Methylation of Polo-Like Kinase 1 (PLK1) in Colorectal Cancer

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