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目的:探讨老年高血压患者脉压指数(PPI)与颈动脉内膜-中层厚度(IMT)的相关性。方法:选取104例老年(年龄≥60岁)高血压患者,多普勒超声仪测定IMT,据其分为IMT正常组、IMT增厚组和斑块形成组三组,收集一般临床资料,计算PPI。结果:IMT增厚组及斑块形成组收缩压(SBP)、脉压(PP)、PPI、TC、LDL-C均高于IMT正常组,HDL-C低于IMT正常组,差异有统计学意义。IMT增厚组与斑块形成组比较差异亦有统计学意义。相关分析显示IMT与SBP、PP、PPI、TC及LDL-C呈正相关,与HDL-C呈负相关。结论:PPI与IMT密切相关。
Objective: To investigate the relationship between pulse pressure index (PPI) and carotid intima-media thickness (IMT) in elderly patients with hypertension. Methods: A total of 104 elderly hypertensive patients (aged ≥60 years) were enrolled in this study. IMT was measured by Doppler sonography and divided into IMT normal group, IMT thickening group and plaque formation group. The clinical data were collected and calculated PPI. Results: SBP, PP, PPI, TC and LDL-C in IMT thickening group and plaque formation group were higher than those in normal IMT group and HDL-C group was lower than IMT normal group significance. IMT thickened group and plaque formation group also had significant differences. Correlation analysis showed that IMT was positively correlated with SBP, PP, PPI, TC and LDL-C and negatively correlated with HDL-C. Conclusion: PPI is closely related to IMT.