我科自1977年初采用液氮低温治疗口腔颌面部十余种疾病500余例,获得较好效果,在此基础上自1978年起对口腔颌面部恶性肿瘤进行冷冻治疗,或作为综合治疗手段之一,也获得较好效果。如对一例上腭恶性黑色素瘤 T_4N_(16)M_0患者进行冷冻治疗后,患侧颌下淋巴结明显肿大,似鸡蛋,质韧,稍能活动,无压痛,患者自诉冷冻后精神,食 In our department, we have used liquid nitrogen cryogenic to treat more than 500 cases of oral and maxillofacial diseases at the beginning of 1977 and achieved better results. On this basis, we have performed cryotherapy on oral and maxillofacial malignancies since 1978, or as a comprehensive treatment. One of the means is also getting better results. For example, when a patient with malignant melanoma of the upper eyelid T_4N_(16)M_0 was treated with cryotherapy, the affected submandibular lymph nodes were swollen, like eggs, tough, slightly active, no tenderness, and the patient complained about the spirit after freezing.