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目的观察奥扎格雷钠联合低分子肝素治疗短暂性脑缺血发作的临床疗效。方法将58例短暂性脑缺血发作患者随机分为肝素对照组30例和联合治疗组28例。肝素对照组采用低分子肝素治疗,联合治疗组采用奥扎格雷钠和低分子肝素联合治疗。结果与肝素对照组比较,治疗后联合治疗组血浆黏度和纤维蛋白原均有明显改善(P<0.01);联合治疗组总有效率92.86%,对照组总有效率76.67%,2组疗效比较有显著性差异(P<0.05)。结论奥扎格雷钠联合低分子肝素治疗短暂性脑缺血发作有良好的疗效。
Objective To observe the clinical efficacy of sodium ozagrel combined with low molecular weight heparin in the treatment of transient ischemic attack. Methods Fifty-eight patients with transient ischemic attack were randomly divided into heparin control group (n = 30) and combination therapy group (n = 28). Heparin control group with low molecular weight heparin treatment, combined treatment group with sodium ozagrel and low molecular weight heparin combined treatment. Results Compared with the heparin control group, the plasma viscosity and fibrinogen of the combined treatment group were significantly improved after treatment (P <0.01). The total effective rate was 92.86% in the combined treatment group and 76.67% in the control group. There was a significant difference between the two groups Significant difference (P <0.05). Conclusion Ozagrel sodium combined with low molecular weight heparin in the treatment of transient ischemic attack has a good effect.