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目的:观察异丙酚复合氯胺酮静脉麻醉用于小儿扁桃体切除术的效果,并与氯胺酮与羟丁酸钠复合进行对比。方法:择期手术患者48例,随机分为实验组(n=24),对照组(n=24)。异丙酚诱导剂量为2mg/kg,维持4mg·kg~(-1)·h~(-1),氯胺酮诱导剂量2mg/kg,连续监测MAP,HR及sPO_2,记录起效时间和清醒时间。结果:实验组起效时间和清醒时间明显短于对照组(P<0.01),两组均有sPO_2下降,无统计学差异(P>0.05)。结论:在小儿扁桃体切除术中应用异丙酚复合氯胺酮静脉麻醉是较好的麻醉选择。
Objective: To observe the effect of propofol combined with ketamine intravenous anesthesia in pediatric tonsillectomy and to compare with ketamine and sodium oxybate. Methods: Forty-eight patients undergoing elective surgery were randomly divided into experimental group (n = 24) and control group (n = 24). Propofol induced dose was 2mg / kg, maintaining 4mg · kg -1 · h -1, ketamine induction dose 2mg / kg, continuous monitoring of MAP, HR and sPO_2, recording the onset time and awake time. Results: The onset time and the awake time of the experimental group were significantly shorter than those of the control group (P <0.01). The sPO_2 of both groups decreased, with no significant difference (P> 0.05). CONCLUSIONS: Propofol combined with ketamine intravenous anesthesia is a good anesthetic option in pediatric tonsillectomy.