血管紧张素转换酶2是一种能够代谢多种肽类底物的多效单羧肽酶,其主要功能是水解血管紧张素Ⅱ生成血管紧张素(1～7)。血管紧张素(1～7)具有舒张血管、保护内皮细胞等作用,这些作用可以抑制动脉粥样硬化病变。近年来,血管紧张素转换酶2在动脉粥样硬化中所起的作用成为研究的热点,并取得了一些成果。 Angiotensin-converting enzyme 2 is a multi-functional monocarboxypeptidase capable of metabolizing various peptide substrates. Its main function is to hydrolyse angiotensin II to produce angiotensin (1-7). Angiotensin (1-7) can relax blood vessels, protect endothelial cells and other effects, these effects can inhibit atherosclerotic lesions. In recent years, angiotensin-converting enzyme 2 in the role of atherosclerosis has become a research hotspot, and achieved some results.