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低分子右旋糖酐是一种水溶性多糖类高分子聚合物,具有扩充血容量,改善微循环,影响凝血机制,利尿消肿的药理作用。本品在临床上多用于抢救各种原因引起的休克,防治缺血性血管疾病,如脑血栓形成、心绞痛等,还可治疗流行性出血热,预防急性肾功能衰竭,(亦有人报道此药可导致肾功能衰竭),以及腹部手术后炎症和肠粘连。自1947年Rosenqvit将右旋糖酐作为血浆代用品用手临床后,1957年至1989年2月,综合部分文献报道,国人共发生低分子右旋糖酐过敏反应24例,其中
Low molecular weight dextran is a kind of water-soluble polysaccharide polymer, which has the pharmacological effects of expanding blood volume, improving microcirculation, affecting blood coagulation mechanism and diuretic swelling. This product is used clinically to rescue a variety of causes of shock, prevention and treatment of ischemic vascular diseases such as cerebral thrombosis, angina pectoris, but also for the treatment of epidemic hemorrhagic fever, prevention of acute renal failure, (it was also reported that the drug Can cause kidney failure), as well as post-abdominal surgery inflammation and intestinal adhesion. Since 1947, Rosenqvit dextran as a plasma substitute by hand after clinical, from 1957 to February 1989, a comprehensive part of the literature reported that the country a total of 24 cases of low molecular weight dextran allergic reactions, of which