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1953年,德国学者Dost在其所著的“血药浓度——动力学”一书中,首先提出了药物代谢动力学”这一概念。自此以后,有关药物代谢动力学的研究有了迅速的发展,其大致过程如下:
In 1953, the German scholar Dost first proposed the concept of pharmacokinetics in his book Blood Concentration - Kinetics. Since then, the study of pharmacokinetics has been rapid. The general process of development is as follows: