目的研究孕妇行沙眼衣原体感染筛查和干预对母婴结局影响。方法对孕中晚期妇女进行沙眼衣原体筛查,并根据是否有沙眼衣原体感染及是否接受治疗分为三组。阳性未治疗者为阳性对照组(A组),阳性并接受治疗者为治疗组(B组),阴性者为阴性对照组(C组)。观察三组胎膜早破、早产、产褥病率、绒毛膜羊膜炎及新生儿感染比率。结果治疗组胎膜早破(18.8%)、产褥病率(4.4%)、绒毛膜羊膜炎(40.2%)、新生儿感染率(顺产10.2%、剖宫产0.8%)及早产(1.2%)较阳性对照组低,且差异均有统计学意义(P<0.05)。结论孕期衣原体筛查和干预可降低母婴并发症,具有重要的临床意义。 Objective To study the influence of screening and intervention of Chlamydia trachomatis in pregnant women on maternal and infant outcomes. Methods The screening of Chlamydia trachomatis in mid-second trimester women was divided into three groups according to whether there were Chlamydia trachomatis infections and whether they were treated or not. The positive untreated patients were positive control group (group A), those who were positive and treated were treated group (group B), while the negative ones were negative control group (group C). Three groups of premature rupture of membranes, premature labor, puerperal morbidity, chorioamnionitis and neonatal infection rate were observed. Results The incidence of premature rupture of membranes (18.8%), puerperal morbidity (4.4%), chorioamnionitis (40.2%), neonatal infection (10.2% of births, 0.8% of cesarean section) ) Was lower than the positive control group, and the differences were statistically significant (P <0.05). Conclusion Chlamydia screening and intervention during pregnancy can reduce maternal and child complications, has important clinical significance.