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急性多发性神经根炎及慢性(再发性)多发性神经根炎,都是周围神经脱髓鞘疾病,其发病机理多认为与变态反应有关。病理形态学的研究中,对脊髓神经采用纤维分离法进行观察分析是极为重要的。作者研究了15例多发性神经根炎,其中急性型8例,慢性及慢性再发型7例。年龄16～65岁。男11例,女4例。发病至活检或尸检的时间为7天～36个月。13例非神经系统疾病死亡者做尸检对照。两组各取腰髓神经前根和腓肠神经分离成70～110条单一的神经纤维进行形态观察。发现:①在同一条神经纤维中节段性脱髓鞘和再生是同时进行的;②腰髓神经前根的改变主要表现为节段性脱髓鞘,一般见不到轴索变性;③腓肠神经的改变除了节段性脱髓鞘之外,还
Acute multiple nerve root inflammation and chronic (recurrent) multiple nerve root inflammation, are peripheral nerve demyelinating disease, its pathogenesis and more that with the allergic reaction. In the study of pathomorphology, it is very important to observe and analyze the spinal cord nerve by fiber separation method. The authors studied 15 cases of multiple nerve root inflammation, of which 8 cases of acute type, chronic and chronic re-7 cases. Age 16 to 65 years old. 11 males and 4 females. The onset of time to biopsy or autopsy for 7 days to 36 months. Thirteen non-neurological disease deaths were autopsy control. The two groups were taken from the anterior root of the lumbar cord and the sural nerve into 70 ~ 110 single nerve fibers morphological observation. Found: ① in the same nerve fibers segmental demyelination and regeneration are carried out simultaneously; ② lumbar nerve root anterior changes mainly manifested as segmental demyelination, axonal degeneration is generally not seen; ③ Philippians Intestinal nerve changes in addition to segmental demyelination, but also