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目的观察盐酸伐昔洛韦分散片金喉健喷剂联合治疗儿童疱疹性咽峡炎的疗效。方法治疗组54例,盐酸伐昔洛韦分散片10 mg/(kg.d),分2次空腹口服,联合金喉健喷剂喷患处;对照组52例,利巴韦林颗粒剂10~15 mg/(kg.d),分3次空腹口服,联合金喉健喷剂喷患处,对比观察两组痊愈率、痊愈时间。结果治疗组痊愈率为85.2%,与对照组比较差异有显著性(P<0.05)。从开始治疗至痊愈时间,治疗组平均为(4.43±1.57)d,较对照组平均(6±1.67)d有显著差异(P<0.05)。不良反应轻微,均为轻度恶心、腹痛或胃部不适等,未发现其他不良反应。结论伐昔洛韦与金喉健喷剂联合治疗儿童疱疹性咽峡炎疗效满意、用药方便。
Objective To observe the curative effect of combined treatment with Vagilofloxacin Dispersible Tablets Jinhuijian Spray on children herpes angina. Methods 54 cases of treatment group, valaciclovir hydrochloride dispersible tablets 10 mg / (kg.d), 2 times fasting oral administration, combined with Golden Throat spray spray the affected area; control group of 52 patients, ribavirin granules 10 ~ 15 mg / (kg.d), 3 times fasting oral administration, combined with Golden Throat spray spray the affected area, compared the two groups cure rate, recovery time. Results The cure rate of the treatment group was 85.2%, which was significantly different from the control group (P <0.05). From the beginning of treatment to the recovery time, the treatment group averaged (4.43 ± 1.57) d, which was significantly different from the control group (6 ± 1.67) d (P <0.05). Minor adverse reactions, were mild nausea, abdominal pain or stomach upset, etc., found no other adverse reactions. Conclusion Valaciclovir and Jinhujian Spray in the treatment of children with herpes angina have satisfactory results and convenient medication.