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目的分析3种不同用药方案治疗儿童哮喘的治疗效果,探讨儿童哮喘的最佳治疗方法。方法选择我院治疗294例儿童哮喘病例作为研究对象,随机分成3组,即对照组98例(单用布地奈德氧气雾化吸入)、氧气驱动雾化吸入联合治疗(氧气驱动联合组)98例和超声雾化吸入联合治疗(超声联合组)98例,对比各组临床疗效以及临床症状消失用时。结果氧气驱动雾化吸入组临床总有效率(95.92%)显著高于其他2组,超声雾化吸入组临床总有效率(85.71%)显著高于对照组,氧气驱动雾化吸入组临床症状消失用时最短(4.06±0.81)d,其次为超声雾化吸入组(5.12±0.89)d,经统计学分析,P均<0.05,具有显著性差异。结论孟鲁司特钠联合布地奈德是儿童哮喘的有效用药方案,氧气驱动雾化吸入给药更有利于药物吸收,提高治疗效果,建议推广。
Objective To analyze the therapeutic effects of three different drug regimens on childhood asthma and explore the best treatment for childhood asthma. Methods A total of 294 children with asthma were selected as study subjects and randomly divided into three groups: control group (98 cases), inhalation of budesonide alone (oxygen inhalation alone) and oxygen inhalation combined inhalation therapy group Cases and ultrasonic atomization inhalation combined therapy (ultrasound combined group) 98 cases, the clinical efficacy of each group compared with the disappearance of clinical symptoms. Results The total effective rate (95.92%) in aerosol inhalation group was significantly higher than that in the other two groups. The total effective rate (85.71%) in aerosol inhalation group was significantly higher than that in control group. The clinical symptoms disappeared With the shortest time (4.06 ± 0.81) d, followed by ultrasonic inhalation group (5.12 ± 0.89) d, the statistical analysis, P <0.05, with significant differences. Conclusion Combination of montelukast and budesonide is an effective drug regimen for asthma in children. Oxygen-driven aerosol inhalation is more conducive to drug absorption and improve the therapeutic effect, and it is recommended to promote.